Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP14 | P31944 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP5 | P51878 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | CASP12 | Q6UXS9 | 1/20 | 0.38 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2623721 | 0.94 | ACHE (0.42) | EGFRPDGFRBKDRCA4LTA4H | |
| SCHEMBL2623728 | 0.85 | L3MBTL1 (0.37) | KDM4EKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26044334 | 0.80 | MEN1 (0.39) | KMT2ACSF1R | |
| SCHEMBL2623720 | 0.78 | ALDH1A1 (0.33) | KDM4EKMT2ATP53ALDH1A1LMNA | |
| SCHEMBL26044051 | 0.77 | HPGD (0.35) | EGFRCA4HPGDKMT2ATP53 | |
| SCHEMBL26043018 | 0.77 | KCNN4 (0.36) | KDM4EHPGDALDH1A1LMNAMAPT | |
| SCHEMBL26043057 | 0.77 | KCNN4 (0.36) | KDM4EHPGDALDH1A1LMNAMAPT | |
| SCHEMBL2623761 | 0.77 | KDM4C (0.39) | CASP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL26043030 | 0.77 | MEN1 (0.36) | KMT2A | |
| SCHEMBL13720899 | 0.77 | CA4 (0.59) | CA4LTA4HKDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120091884-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AT) | 2012-04-19 | — | — | US | disclosed |
| WO-2010132953-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120091884-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | HSD17B2, CYP1A2, HSD17B1 | EGFR 3681/4885PDGFRB 4559/4885KDR 2897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.