SCHEMBL2623728

SCHEMBL2623728

c1ccc(N(C2=NC3=NC(N(c4ccccc4)c4ccccc4)=NC4=NC(N(c5ccccc5)c5ccccc5)=NC(=N2)N34)c2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
KDM4E B2RXH2 1/20 0.37
TSHR P16473 2/20 0.35
POLB P06746 1/20 0.32
MEN1 O00255 2/20 0.31
CRHBP P24387 2/20 0.31
KMT2A Q03164 2/20 0.31
CRHR2 Q13324 2/20 0.31
ATM Q13315 1/20 0.31
TLR9 Q9NR96 1/20 0.31
KCNA3 P22001 1/20 0.31
MAPK1 P28482 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2623720 0.85 ALDH1A1 (0.33) L3MBTL1ALDH1A1MAPTTDP1CYP1A2
SCHEMBL2632320 0.85 TSHR (0.39) MAPTTSHRPOLBMEN1CRHBP
SCHEMBL2632428 0.85 CYP3A4 (0.40) L3MBTL1ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL2632325 0.85 EGFR (0.40) L3MBTL1ALDH1A1MAPTKDM4EKMT2A
SCHEMBL16838176 0.83 SLC6A2 (0.34)
SCHEMBL2623724 0.83 CHRM5 (0.39) MAPTSMN1; SMN2
SCHEMBL2623725 0.81 SIGMAR1 (0.40) L3MBTL1ALDH1A1MAPTTDP1CYP1A2
SCHEMBL2623759 0.81 MEN1 (0.34) ALDH1A1CYP2C9TSHRMEN1KMT2A
SCHEMBL26043032 0.81 SMN1; SMN2 (0.31) L3MBTL1MAPTMEN1KMT2AMAPK1
SCHEMBL26043021 0.81 MEN1 (0.31) L3MBTL1MAPTMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
EP-3706182-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kyushu University National University Corporation (JP) 2020-09-09 EP disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
US-9985215-B2 Light-emitting material, and organic light-emitting element KYULUX, INC. (JP) 2018-05-29 US disclosed
US-9985215-B2 Light-emitting material, and organic light-emitting element KYULUX, INC. (JP) 2018-05-29 US disclosed
EP-2980877-B1 ORGANIC ELECTROLUMINESCENT ELEMENT KYULUX INC (JP) 2017-11-29 EP disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-9066410-B2 Organic electronic device MERCK PATENT GMBH (DE) 2015-06-23 US disclosed
US-9066410-B2 Organic electronic device MERCK PATENT GMBH (DE) 2015-06-23 US disclosed
US-20150048338-A1 LIGHT-EMITTING MATERIAL, AND ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2015-02-19 US disclosed
US-20150048338-A1 LIGHT-EMITTING MATERIAL, AND ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2015-02-19 US disclosed
EP-2824159-A1 LIGHT-EMITTING MATERIAL, AND ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2015-01-14 EP disclosed
US-20120091884-A1 HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AT) 2012-04-19 US disclosed
US-20120091884-A1 HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AT) 2012-04-19 US disclosed
WO-2010132953-A1 HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 L3MBTL1 297/4885ALDH1A1 2419/4885MAPT 643/4885
US-20120091884-A1 HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE HSD17B2, CYP1A2, HSD17B1 L3MBTL1 4792/4885ALDH1A1 15/4885MAPT 3008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.