Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 4/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20565216 | 0.88 | BTN3A1 (0.40) | BTN3A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26324890 | 0.77 | ALDH1A1 (0.39) | KMT2AMEN1SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL26324920 | 0.77 | TSHR (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4KMT2A | |
| SCHEMBL26324865 | 0.74 | TSHR (0.38) | BTN3A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26324941 | 0.74 | TSHR (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4KMT2A | |
| SCHEMBL14852043 | 0.71 | SMN1; SMN2 (0.43) | KMT2AMEN1SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL26324800 | 0.70 | TSHR (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4KMT2A | |
| SCHEMBL3342299 | 0.70 | MEN1 (0.39) | KMT2AMEN1SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL26324873 | 0.69 | TSHR (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4KMT2A | |
| SCHEMBL14851873 | 0.69 | RAB9A (0.52) | KMT2AMEN1SMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | BTN3A1 1491/4885CHRNB2 1465/4885CHRNB4 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.