Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24303424 | 0.83 | ADRA2A (0.53) | ADRB1ADRB2ADRB3HIF1ACYP2D6 | |
| SCHEMBL21216528 | 0.80 | ADRB1 (0.44) | ADRB1ADRB2ADRB3HIF1AMAPT | |
| SCHEMBL29786456 | 0.79 | CES2 (0.44) | ADRB1ADRB2ADRB3MAPTKDM4E | |
| SCHEMBL24370650 | 0.79 | CES2 (0.44) | ADRB1ADRB2ADRB3MAPTKDM4E | |
| SCHEMBL22957657 | 0.78 | GAA (0.54) | ADRB1ADRB2ADRB3HIF1ACYP2D6 | |
| SCHEMBL22957831 | 0.78 | GAA (0.54) | ADRB1ADRB2ADRB3HIF1ACYP2D6 | |
| SCHEMBL828538 | 0.76 | HIF1A (0.52) | ADRB1ADRB2ADRB3HIF1ACYP2D6 | |
| SCHEMBL28415306 | 0.75 | CES2 (0.44) | ADRB1ADRB3ADRA2AADRA2BADRA2C | |
| SCHEMBL31074206 | 0.75 | CES2 (0.44) | ADRB1ADRB3ADRA2AADRA2BADRA2C | |
| SCHEMBL12312536 | 0.74 | CYP2D6 (0.54) | ADRB1ADRB2HIF1ACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767322-B2 | Triazolopyridinyl compounds as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767322-B2 | Triazolopyridinyl compounds as kinase inhibitors | RIPK1, RIPK3, RIPK4 | ADRB1 2950/4885ADRB2 3794/4885ADRB3 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.