Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26326857 | 1.00 | L3MBTL1 (0.42) | L3MBTL1MCOLN3MAPTNPSR1TDP1 | |
| SCHEMBL12879195 | 0.81 | HRH3 (0.41) | MGLLP2RX7SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25191132 | 0.81 | MAP3K12 (0.40) | L3MBTL1MAPTNPSR1TDP1LMNA | |
| SCHEMBL25855613 | 0.81 | GAA (0.46) | L3MBTL1ADRB1ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL19001023 | 0.81 | HSD11B1 (0.40) | MGLL | |
| SCHEMBL25855534 | 0.81 | GAA (0.46) | L3MBTL1ADRB1ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL22442324 | 0.76 | MGLL (0.47) | MAPTTDP1MGLLALDH1A1POLB | |
| SCHEMBL12143001 | 0.75 | HTT (0.50) | MAPTNPSR1TDP1LMNAALDH1A1 | |
| SCHEMBL1108634 | 0.75 | MAP3K12 (0.44) | L3MBTL1MCOLN3MAP3K12 | |
| SCHEMBL25196170 | 0.75 | MEN1 (0.46) | MAPTLMNAADRB1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767316-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767316-B2 | Non-fused thiophene derivatives and their uses | FTH1, SLC40A1, FECH | L3MBTL1 969/4885MCOLN3 3783/4885MAPT 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.