Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595507 | 0.87 | MGMT (0.48) | CYP1A2CYP2C9CYP2C19NUDT1L3MBTL1 | |
| SCHEMBL30026947 | 0.87 | MGMT (0.48) | CYP1A2CYP2C9CYP2C19NUDT1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL25369331 | 0.85 | MGMT (0.47) | CYP1A2CYP2C9CYP2C19NUDT1L3MBTL1 | |
| SCHEMBL26329035 | 0.85 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19TLR8BCHE | |
| SCHEMBL6175355 | 0.80 | L3MBTL1 (0.46) | CYP1A2CYP2C9CYP2C19TLR8TLR7 | |
| SCHEMBL30271317 | 0.80 | L3MBTL1 (0.46) | CYP1A2CYP2C9CYP2C19TLR8TLR7 | |
| SCHEMBL13348569 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19TLR8BCHE | |
| SCHEMBL23274021 | 0.79 | NUDT1 (0.49) | NUDT1L3MBTL1TSHRALDH1A1MAPK1 | |
| SCHEMBL26329073 | 0.78 | TLR8 (0.43) | CYP1A2CYP2C19TLR8TLR7BCHE | |
| SCHEMBL29210862 | 0.76 | NUDT1 (0.41) | CYP1A2CYP2C9CYP2C19NUDT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | CRBN, CBL, STUB1 | CYP1A2 4609/4885CYP2C9 4807/4885CYP2C19 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.