Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31108038 | 0.87 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1LMNATSHRHPGD | |
| SCHEMBL20595413 | 0.87 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1LMNATSHRHPGD | |
| SCHEMBL26329033 | 0.85 | LTA4H (0.41) | TLR8L3MBTL1ALDH1A1LMNATSHR | |
| SCHEMBL26329102 | 0.78 | CYP1A2 (0.46) | TLR8TLR7L3MBTL1ALDH1A1LMNA | |
| SCHEMBL25447041 | 0.75 | DGAT1 (0.43) | TLR8TLR7L3MBTL1ALDH1A1LMNA | |
| SCHEMBL12745447 | 0.72 | HTR1A (0.63) | L3MBTL1ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL31390651 | 0.71 | LMNA (0.44) | L3MBTL1ALDH1A1LMNATSHRHPGD | |
| SCHEMBL29000550 | 0.71 | HTR1A (0.57) | L3MBTL1ALDH1A1LMNATSHRHPGD | |
| SCHEMBL2520179 | 0.71 | LTA4H (0.50) | TLR8L3MBTL1ALDH1A1LMNATSHR | |
| SCHEMBL29872143 | 0.71 | LIPE (0.53) | L3MBTL1ALDH1A1LMNATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | CRBN, CBL, STUB1 | TLR8 3617/4885TLR7 4270/4885L3MBTL1 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.