Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 9/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | USP4 | Q13107 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18029366 | 0.83 | MAPT (0.48) | ADAM17MAP2K2MAP2K1ALDH1A1KDM4E | |
| SCHEMBL29311771 | 0.83 | SPR (0.40) | ADAM17SMYD3MMP9MMP8CMA1 | |
| SCHEMBL14011134 | 0.79 | GPR84 (0.55) | ADAM17SMYD3MMP9MMP8CMA1 | |
| SCHEMBL31158207 | 0.79 | GPR84 (0.55) | ADAM17SMYD3MMP9MMP8CMA1 | |
| SCHEMBL14035189 | 0.79 | GPR84 (0.55) | ADAM17SMYD3MMP9MMP8CMA1 | |
| SCHEMBL25660770 | 0.79 | GPR84 (0.55) | ADAM17SMYD3MMP9MMP8CMA1 | |
| SCHEMBL26329049 | 0.75 | MMP9 (0.48) | ADAM17MMP9KDM4EMMP2 | |
| SCHEMBL18029145 | 0.74 | MAPT (0.45) | ADAM17MAP2K2MAP2K1ALDH1A1DUSP3 | |
| SCHEMBL13881435 | 0.71 | PPARG (0.43) | MMP9MMP2 | |
| SCHEMBL23677942 | 0.69 | ADAM17 (0.52) | ADAM17MMP9MMP8ALDH1A1DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229090-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-11 | — | — | US | disclosed |
| US-20230287466-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH (US) | 2023-09-14 | — | — | US | disclosed |