Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 2/20 | 0.37 |
| ▸ | GNPAT | O15228 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 8/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26080391 | 0.92 | PTPN1 (0.37) | PARP1PARP3MMP2MMP8MMP12 | |
| SCHEMBL18381353 | 0.92 | PTPN1 (0.37) | PARP1PARP3MMP2MMP8MMP12 | |
| SCHEMBL2633257 | 0.89 | GNPAT (0.41) | GNPATMMEACE | |
| SCHEMBL2319309 | 0.88 | PARP1 (0.38) | PARP1PARP3MMP2MMP8MMP12 | |
| SCHEMBL30918646 | 0.85 | SLC15A2 (0.35) | PARP1PARP3 | |
| SCHEMBL2633324 | 0.84 | ACE (0.36) | GNPATACE | |
| SCHEMBL7281103 | 0.84 | PARP1 (0.50) | PARP1PARP3MMP2MMP8MMP12 | |
| SCHEMBL9664390 | 0.84 | XDH (0.43) | — | |
| SCHEMBL20230288 | 0.83 | MMP8 (0.40) | MMP2MMP8MMP12MMP13 | |
| SCHEMBL9665952 | 0.83 | SLC6A5 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668973-B2 | Components for producing amphoteric liposomes | MARINA BIOTECH, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20140227345-A1 | COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES | MARINA BIOTECH, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8580297-B2 | Components for producing amphoteric liposomes | MARINA BIOTECH, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120100205-A1 | COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES | MARINA BIOTECH, INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140227345-A1 | COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES | PHOSPHO1, SGMS1, CHMP4B | PARP1 4184/4885PARP3 4695/4885MMP2 2164/4885 |
| US-20120100205-A1 | COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES | PHOSPHO1, SGMS1, CHMP4B | PARP1 4184/4885PARP3 4695/4885MMP2 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.