Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carnosine SCHEMBL1161010 | 0.89 | ITGB3 (0.41) | ITGB3ITGA2B | |
| Carnosine SCHEMBL33768 | 0.89 | ITGB3 (0.41) | ITGB3ITGA2B | |
| Carnosine SCHEMBL33769 | 0.89 | ITGB3 (0.41) | ITGB3ITGA2B | |
| Carnosine SCHEMBL3904964 | 0.89 | ITGB3 (0.41) | ITGB3ITGA2B | |
| SCHEMBL30918646 | 0.89 | SLC15A2 (0.35) | PARP1PARP3MMP1FCER2 | |
| Carnosine SCHEMBL1641133 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2B | |
| Carnosine SCHEMBL11033195 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2B | |
| Carnosine SCHEMBL308693 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2B | |
| Carnosine SCHEMBL134705 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL2633410 | 0.88 | PARP1 (0.37) | PARP1PARP3MMP2MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011235-A1 | SKIN MOISTURE RETENTION COMPOSITION AND SKIN BEAUTY METHOD THEREFOR | 久文股份有限公司 | 2020-01-16 | — | — | WO | claimed |
| WO-2020011235-A1 | SKIN MOISTURE RETENTION COMPOSITION AND SKIN BEAUTY METHOD THEREFOR | 久文股份有限公司 | 2020-01-16 | — | — | WO | disclosed |
| CN-106795122-B | Nitric Oxide Donor Carnosine Compounds | 尼科斯股份有限公司 | 2019-09-27 | — | — | CN | disclosed |
| US-10093696-B2 | Nitric oxide donating carnosine compounds | NICOX SCIENCE IRELAND (IE) | 2018-10-09 | — | — | US | disclosed |
| US-20170291920-A1 | NITRIC OXIDE DONATING CARNOSINE COMPOUNDS | NICOX SA (FR) | 2017-10-12 | — | — | US | disclosed |
| CN-106795122-A | Nitric oxide donor carnosine compounds | 尼科斯科学爱尔兰公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-2993172-B1 | Nitric oxide donating carnosine compounds | NICOX SCIENCE IRELAND (IE) | 2017-04-19 | — | — | EP | disclosed |
| WO-2016034619-A1 | NITRIC OXIDE DONATING CARNOSINE COMPOUNDS | NICOX SCIENCE IRELAND (IE) | 2016-03-10 | — | — | WO | disclosed |
| EP-2993172-A1 | Nitric oxide donating carnosine compounds | Nicox Science Ireland (IE) | 2016-03-09 | — | — | EP | disclosed |
| US-8293943-B1 | Prevention of cellular senescence in mammals by natural peptide complexes | ISLAND KINETICS, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20120264696-A1 | PREVENTION OF CELLULAR SENESCENCE IN MAMMALS BY NATURAL PEPTIDE COMPLEXES | ISLAND KINETICS INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-8258343-B1 | Prevention of cellular senescence in mammals by natural peptide complexes | ISLAND KINETICS, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-8212076-B2 | Prevention of cellular senescence in mammals by natural peptide complexes | Covalence, Inc. (US) | 2012-07-03 | — | — | US | disclosed |
| US-20110190202-A1 | Prevention of Cellular Senescence in Mammals by Natural Peptide Complexes | ISLAND KINETICS INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291920-A1 | NITRIC OXIDE DONATING CARNOSINE COMPOUNDS | NOS1, NOS2, NOS3 | PARP1 673/4885PARP3 1913/4885HDAC6 2489/4885 |
| US-10093696-B2 | Nitric oxide donating carnosine compounds | NOS1, NOS2, NOS3 | PARP1 673/4885PARP3 1913/4885HDAC6 2489/4885 |
| US-20120264696-A1 | PREVENTION OF CELLULAR SENESCENCE IN MAMMALS BY NATURAL PEPTIDE COMPLEXES | COL14A1, TP53, CUTA | PARP1 1421/4885PARP3 2562/4885HDAC6 534/4885 |
| US-20110190202-A1 | Prevention of Cellular Senescence in Mammals by Natural Peptide Complexes | COL14A1, TP53, CUTA | PARP1 1421/4885PARP3 2562/4885HDAC6 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.