SCHEMBL26344002

SCHEMBL26344002

c1cc2c3ncccc3n3c4ccccc4c4c5ccsc5c(c1)c2c43

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
LMNA P02545 1/20 0.34
ADORA1 P30542 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MPI P34949 1/20 0.33
ALDH1A1 P00352 1/20 0.32
BRD4 O60885 1/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32
GABRA4 P48169 1/20 0.32
GABRE P78334 1/20 0.32
GABRA6 Q16445 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26343984 0.93 KDM4E (0.36) KDM4ELMNAADORA1L3MBTL1MPI
SCHEMBL26343936 0.87 KDM4E (0.37) KDM4ELMNAL3MBTL1MPIBRD4
SCHEMBL26344011 0.83 GABRP (0.33) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL26344065 0.80 KDM4E (0.34) KDM4EALDH1A1NLRP3ACHERORC
SCHEMBL26344028 0.78 KDM4E (0.31) KDM4EL3MBTL1MPIGABRPGABRD
SCHEMBL26344019 0.77 KDM4E (0.31) KDM4EL3MBTL1MPIBRD4GABRP
SCHEMBL26344080 0.77 LMNA (0.38) LMNANLRP3ACHE
SCHEMBL26343993 0.77 GABRP (0.31) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL26343896 0.73 LMNA (0.38) KDM4ELMNAL3MBTL1MPIALDH1A1
SCHEMBL26344157 0.72 KMT2A (0.35) KDM4ELMNAL3MBTL1MPIALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF CRY1, LEF1, PIEZO1 KDM4E 743/4885LMNA 1501/4885ADORA1 1837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.