SCHEMBL263447

SCHEMBL263447

C[N+](C)(C)[C@H](CCc1nc(C[C@H](N)C(=O)O)c[nH]1)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP1A2 P05177 1/20 0.34
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
TSHR P16473 2/20 0.32
BLM P54132 2/20 0.32
PMP22 Q01453 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
MPO P05164 1/20 0.32
HIF1A Q16665 1/20 0.32
TNF P01375 1/20 0.31
TPH1 P17752 1/20 0.31
ALPI P09923 1/20 0.31
PKM P14618 1/20 0.31
PTGS1 P23219 1/20 0.31
XIAP P98170 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL849757 0.83 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL8001783 0.83 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL4453493 0.81 SLC7A5 (0.36) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL4453499 0.81 SLC7A5 (0.36) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL30443813 0.81 SLC7A5 (0.41) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL29022742 0.81 SLC7A5 (0.41) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL2381464 0.80 CYP3A4 (0.34) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL31369905 0.79 SLC7A5 (0.44) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL233540 0.78 SLC7A5 (0.39) SLC7A5CYP3A4CYP1A2KDM4ELMNA
SCHEMBL29022786 0.78 SLC7A5 (0.39) SLC7A5CYP3A4CYP1A2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025226608-A1 IMMUNOTOXIN-ARMORED IMMUNE EFFECTOR CELLS AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2025-10-30 WO claimed
EP-4096715-A1 COMPOSITIONS COMPRISING LINEAR POLYRIBONUCLEOTIDES FOR PROTEIN MODULATION AND USES THEREOF Flagship Pioneering Innovations VI, LLC (US) 2022-12-07 EP claimed
US-20220305128-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES FOR PROTEIN MODULATION AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-09-29 US claimed
EP-3986469-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES FOR PROTEIN MODULATION AND USES THEREOF Flagship Pioneering Innovations VI, LLC (US) 2022-04-27 EP claimed
EP-3943939-A1 MODIFICATION-DEPENDENT ACTIVITY ASSAYS Takeda Pharmaceutical Company Limited (JP) 2022-01-26 EP claimed
US-20210325368-A1 METHODS DETERMINING AND TREATING CELLULAR RESISTANCE TO ADP-RIBOSYLATING TOXIN THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2021-10-21 US claimed
WO-2021155177-A1 COMPOSITIONS COMPRISING LINEAR POLYRIBONUCLEOTIDES FOR PROTEIN MODULATION AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2021-08-05 WO claimed
WO-2020257730-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES FOR PROTEIN MODULATION AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2020-12-24 WO claimed
US-20200348308-A1 KITS FOR ANALYSIS USING NUCLEIC ACID ENCODING AND/OR LABEL Encodia, Inc. (US) 2020-11-05 US claimed
CN-105792942-B Collector compositions and methods of making and using the same 佐治亚-太平洋化工品有限公司 2019-04-16 CN claimed
US-7598031-B2 Method for the detection of gene transcripts in blood and uses thereof GENENEWS CORPORATION (CA) 2009-10-06 US claimed
EP-2038415-A1 DPH2 GENE DELETION MUTANT AND USES THEREOF Caruso, Manuel (CA) 2009-03-25 EP claimed
WO-2007143858-A1 DPH2 GENE DELETION MUTANT AND USES THEREOF CARUSO MANUEL (CA) 2007-12-21 WO claimed
EP-1071334-A4 A METHOD FOR EFFICIENT AND HIGHLY SELECTIVE CONTROL OF MICROORGANISMS WHITEHEAD BIOMEDICAL INST (US) 2004-03-10 EP claimed
US-20030078231-A1 Orthomolecular sulpho-adenosylmethionine derivatives with antioxidant properties WILBURN MICHAEL D (US) 2003-04-24 US claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
EP-1071334-A1 A METHOD FOR EFFICIENT AND HIGHLY SELECTIVE CONTROL OF MICROORGANISMS WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2001-01-31 EP claimed
EP-0968282-A2 VECTORS AND METHODS FOR EXPRESSION OF MUTANT PROTEINS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-01-05 EP claimed
WO-1999053762-A1 A METHOD FOR EFFICIENT AND HIGHLY SELECTIVE CONTROL OF MICROORGANISMS MICROBIA, INC. (US) 1999-10-28 WO claimed
WO-1998039425-A2 VECTORS AND METHODS FOR EXPRESSION OF MUTANT PROTEINS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-09-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078231-A1 Orthomolecular sulpho-adenosylmethionine derivatives with antioxidant properties MAT1A, LPO, TPMT SLC7A5 417/4885CYP3A4 2763/4885CYP1A2 2808/4885
US-20030007961-A1 Orthomolecular vitamin E derivatives RBP4, RBP1, VDR SLC7A5 993/4885CYP3A4 2879/4885CYP1A2 3715/4885
US-20220305128-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES FOR PROTEIN MODULATION AND USES THEREOF RNMT, NSUN3, NSUN2 SLC7A5 4056/4885CYP3A4 4876/4885CYP1A2 4882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.