Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.56 |
| ▸ | BACE1 | P56817 | 8/20 | 0.56 |
| ▸ | BCHE | P06276 | 6/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26346363 | 0.85 | HRH4 (0.49) | ACHEBACE1BCHECHRM4CARM1 | |
| SCHEMBL26348556 | 0.81 | HRH4 (0.55) | ACHEBACE1BCHEEBPDHCR7 | |
| SCHEMBL26346156 | 0.76 | MEN1 (0.58) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL26348162 | 0.76 | MEN1 (0.58) | ACHEBACE1BCHEEBPDHCR7 | |
| SCHEMBL27297657 | 0.75 | HRH4 (0.53) | ALDH1A1 | |
| SCHEMBL7841536 | 0.73 | ACHE (0.66) | ACHEBACE1BCHECARM1PRMT6 | |
| SCHEMBL15337848 | 0.73 | GRIN2D (0.51) | CHRM4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4287133 | 0.73 | HRH4 (0.64) | — | |
| SCHEMBL8355347 | 0.73 | ACHE (0.57) | ACHEBACE1BCHECARM1PRMT6 | |
| SCHEMBL7947657 | 0.73 | HTR2C (0.47) | CHRM4GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303512-A1 | MODULATORS OF MYB-MEDIATED TRANSCRIPTION AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303512-A1 | MODULATORS OF MYB-MEDIATED TRANSCRIPTION AND USES THEREOF | MYB, MYBBP1A, MYCBP | ACHE 4510/4885BACE1 4775/4885BCHE 4519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.