Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 6/20 | 0.43 |
| ▸ | BRD4 | O60885 | 5/20 | 0.43 |
| ▸ | BRD7 | Q9NPI1 | 5/20 | 0.43 |
| ▸ | BRD2 | P25440 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TAF1 | P21675 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905844 | 0.76 | BRD9 (0.46) | BRD9BRD4BRD7BRD2ALDH1A1 | |
| SCHEMBL12937497 | 0.74 | CYP3A4 (0.52) | MEN1KMT2AMAPTHTR2AACHE | |
| SCHEMBL22302148 | 0.72 | BRD9 (0.45) | BRD9BRD4BRD7BRD2ALDH1A1 | |
| SCHEMBL19869934 | 0.72 | BRD9 (0.45) | BRD9BRD4BRD7BRD2ALDH1A1 | |
| SCHEMBL19869865 | 0.71 | BRD9 (0.42) | BRD9BRD4BRD7BRD2ALDH1A1 | |
| SCHEMBL22301784 | 0.71 | PTGS2 (0.55) | BRD9BRD4BRD7BRD2ALDH1A1 | |
| SCHEMBL28556635 | 0.70 | BRD9 (0.43) | BRD9BRD4BRD7BRD2SLC6A4 | |
| SCHEMBL10224469 | 0.68 | CA2 (0.61) | ALDH1A1LMNAACHEGAA | |
| SCHEMBL16303509 | 0.68 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19886496 | 0.68 | TUBB1 (0.35) | MEN1KMT2AMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773085-B2 | Methods and compounds for treating disorders | FOGHORN THERAPEUTICS INC. (US) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773085-B2 | Methods and compounds for treating disorders | VHL, TFEB, BECN1 | BRD9 330/4885BRD4 57/4885BRD7 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.