Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.67 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.67 |
| ▸ | EPOR | P19235 | 4/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899072 | 0.80 | ALOX5 (1.00) | ALOX5PTGS1PTGS2ALOX5APEPOR | |
| SCHEMBL3903195 | 0.80 | ALOX5 (1.00) | ALOX5PTGS1PTGS2ALOX5APEPOR | |
| SCHEMBL29808733 | 0.80 | ALOX5 (1.00) | ALOX5PTGS1PTGS2ALOX5APEPOR | |
| SCHEMBL28357772 | 0.75 | KDM4E (0.63) | ALOX5PTGS2LTB4RLTB4R2LMNA | |
| SCHEMBL28357770 | 0.75 | KDM4E (0.63) | ALOX5PTGS2LTB4RLTB4R2LMNA | |
| SCHEMBL9707281 | 0.74 | ALOX5 (0.64) | ALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL27965115 | 0.71 | PAM (0.52) | ALOX5PTGS1PTGS2ALOX5APLMNA | |
| SCHEMBL27965116 | 0.71 | PAM (0.52) | ALOX5PTGS1PTGS2ALOX5APLMNA | |
| SCHEMBL8987031 | 0.71 | TBXAS1 (0.56) | PTGS1LTB4RLTB4R2KDM4EALDH1A1 | |
| SCHEMBL8987027 | 0.71 | TBXAS1 (0.56) | PTGS1LTB4RLTB4R2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773111-B1 | Selective 5-LO inhibitors for the treatment of bronchial asthma | King Faisal University (SA) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773111-B1 | Selective 5-LO inhibitors for the treatment of bronchial asthma | ALOX5, LTC4S, NOX5 | ALOX5 1/4885PTGS1 150/4885PTGS2 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.