Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588733 | 0.76 | SIRT6 (0.47) | SIRT6MAOB | |
| SCHEMBL8167024 | 0.69 | P2RX7 (0.38) | — | |
| SCHEMBL7105124 | 0.67 | L3MBTL1 (0.41) | SIRT6 | |
| SCHEMBL10717957 | 0.64 | TTR (0.31) | — | |
| SCHEMBL7108522 | 0.64 | SMO (0.40) | — | |
| SCHEMBL23417258 | 0.64 | TDP1 (0.41) | MAOB | |
| SCHEMBL15759510 | 0.63 | GSK3B (0.35) | SIRT6 | |
| SCHEMBL22677556 | 0.63 | — | — | |
| SCHEMBL28074220 | 0.63 | — | — | |
| SCHEMBL8260551 | 0.62 | SIRT6 (0.58) | SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143540-A1 | UNIFORM, FUNCTIONALIZED, CROSS-LINKED NANOSTRUCTURES FOR MONITORING pH | MALLINCKRODT LLC (US) | 2011-11-17 | — | — | WO | disclosed |