Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ASPH | Q12797 | 1/20 | 0.30 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28817951 | 0.76 | PIM1 (0.39) | TSHRKMT2AROCK1KDM4E | |
| SCHEMBL2635320 | 0.76 | SIRT6 (0.73) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL2516931 | 0.76 | SIRT6 (0.45) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL2635751 | 0.76 | SIRT6 (0.34) | SIRT6MAOB | |
| SCHEMBL2482296 | 0.76 | SIRT6 (0.45) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL7105124 | 0.75 | L3MBTL1 (0.41) | SIRT6ROCK1 | |
| SCHEMBL590665 | 0.73 | SIRT6 (0.42) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL1811130 | 0.73 | CXCR4 (0.39) | SIRT6ADORA3TSHRMC4RADRA1A | |
| Hydrochloric Acid SCHEMBL27917292 | 0.73 | SIRT6 (0.70) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL589138 | 0.72 | CKS1B (0.46) | SIRT6KMT2AMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666371-A | Sensor assembly with movable skin sensor | 麦迪贝肯有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-111436947-A | Two-piece sensor assembly and method of use | 麦迪贝肯有限公司 | 2020-07-24 | — | — | CN | disclosed |
| US-20140286874-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON, INC. | 2014-09-25 | — | — | US | disclosed |
| EP-2029554-B1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | MEDIBEACON LLC (US) | 2014-03-19 | — | — | EP | disclosed |
| US-20120100078-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MALLINCKRODT LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-8115000-B2 | Pyrazine derivatives and uses thereof in renal monitoring | MALLINCKRODT LLC (US) | 2012-02-14 | — | — | US | disclosed |
| EP-2029554-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | Mallinckrodt, Inc. (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007149479-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | MALLINCKRODT INC. (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140286874-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | CYP3A5, GLS, XDH | SIRT6 1607/4885ADORA3 638/4885TSHR 1940/4885 |
| US-20120100078-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | CYP3A5, GLS, XDH | SIRT6 1607/4885ADORA3 638/4885TSHR 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.