SCHEMBL26358151

SCHEMBL26358151

O=C(O)c1cc(OCc2ccc3ccccc3c2)cc(OCc2ccc3ccccc3c2)c1

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.73
KMT2A Q03164 1/20 0.73
MRGPRX4 Q96LA9 2/20 0.65
NR4A2 P43354 6/20 0.56
GPBAR1 Q8TDU6 2/20 0.56
RAB9A P51151 2/20 0.54
NR4A1 P22736 1/20 0.53
NR4A3 Q92570 1/20 0.53
NPC1 O15118 2/20 0.52
MAPT P10636 1/20 0.52
CYSLTR1 Q9Y271 2/20 0.52
ALOX5 P09917 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6520384 0.88 NR4A2 (0.71) MRGPRX4NR4A2GPBAR1RAB9ANR4A1
SCHEMBL1426961 0.85 MEN1 (1.00) MEN1KMT2AMRGPRX4NR4A2NR4A1
Hydrochloric Acid SCHEMBL6841086 0.83 MEN1 (0.96) MEN1KMT2AMRGPRX4NR4A2NR4A1
SCHEMBL4265977 0.82 MRGPRX4 (0.56) MEN1KMT2AMRGPRX4NR4A2RAB9A
SCHEMBL862870 0.82 MEN1 (0.93) MEN1KMT2AMRGPRX4NR4A2NR4A1
SCHEMBL31141980 0.81 MEN1 (0.79) MEN1KMT2ANR4A2RAB9ANR4A1
SCHEMBL3599480 0.81 MEN1 (0.79) MEN1KMT2ANR4A2RAB9ANR4A1
SCHEMBL2570286 0.81 MEN1 (0.84) MEN1KMT2AMRGPRX4NR4A2GPBAR1
SCHEMBL9370131 0.80 CASP3 (0.51) MEN1KMT2ANPC1MAPTCYSLTR1
SCHEMBL8994871 0.79 RAB9A (0.67) MRGPRX4RAB9ACYSLTR1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 HIROSHIMA UNIVERSITY (JP) 2024-01-25 US disclosed
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 HIROSHIMA UNIVERSITY (JP) 2024-01-25 US disclosed
EP-4248997-A1 THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR COVID-19 Hiroshima University (JP) 2023-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 PIN1, ACE2, ACE MEN1 3457/4885KMT2A 3733/4885MRGPRX4 2712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.