Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944664 | 0.80 | KDM4E (0.39) | KDM4EHPGDHSD17B10POLBALDH1A1 | |
| SCHEMBL22583086 | 0.79 | ALDH1A1 (0.39) | ATRKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL4535342 | 0.78 | CHRNB2 (0.34) | KDM4EPOLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2636627 | 0.78 | KDM4E (0.34) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL11253057 | 0.78 | CHRNB2 (0.36) | POLBSMN1; SMN2LMNARAB9ACHRNB2 | |
| SCHEMBL18398770 | 0.78 | LMNA (0.39) | KDM4EPOLBSMN1; SMN2LMNARAB9A | |
| SCHEMBL6186076 | 0.77 | HSD17B10 (0.33) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL4632562 | 0.77 | PRKCI (0.38) | ATRKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL28711249 | 0.76 | RAB9A (0.36) | SMN1; SMN2LMNARAB9ATSHRCHRNB2 | |
| SCHEMBL4535346 | 0.74 | SMN1; SMN2 (0.34) | POLBALDH1A1SMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085715-A2 | AZA- AND POLYAZANTHRANYL AMIDES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2001-11-15 | — | — | WO | disclosed |