Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636206 | 0.87 | HTT (0.49) | NPC1RAB9APOLBSMN1; SMN2FFAR1 | |
| SCHEMBL2490121 | 0.83 | NPC1 (0.59) | NPC1RAB9APOLBSMN1; SMN2FFAR1 | |
| SCHEMBL2636713 | 0.82 | RAB9A (0.57) | NPC1RAB9APOLBSMN1; SMN2FFAR1 | |
| SCHEMBL871874 | 0.78 | HTT (0.49) | NPC1RAB9APOLBSMN1; SMN2FFAR1 | |
| SCHEMBL13412435 | 0.75 | SMN1; SMN2 (0.53) | NPC1RAB9APOLBSMN1; SMN2APP | |
| SCHEMBL31658738 | 0.74 | SMN1; SMN2 (0.57) | NPC1RAB9APOLBSMN1; SMN2FFAR1 | |
| SCHEMBL16057847 | 0.73 | LMNA (0.45) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL377060 | 0.73 | NAPRT (0.36) | ALDH1A1MAPT | |
| SCHEMBL5377686 | 0.72 | LTA4H (0.56) | NPC1RAB9AAPPHTTALDH1A1 | |
| SCHEMBL292835 | 0.72 | NPC1 (0.59) | NPC1RAB9APOLBSMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438071-A1 | SUBSTITUTED PYRAZINE (THIO)PYRANS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139657-A1 | SUBSTITUTED PYRAZINE (THIO)PYRANS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-12-09 | — | — | WO | disclosed |