Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ASPH | Q12797 | 1/20 | 0.52 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871874 | 0.87 | HTT (0.49) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL2636714 | 0.82 | NPC1 (0.54) | RAB9ASMN1; SMN2NPC1POLBFFAR1 | |
| SCHEMBL784516 | 0.80 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL10530981 | 0.79 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL2636206 | 0.78 | HTT (0.49) | RAB9ASMN1; SMN2NPC1POLBFFAR1 | |
| SCHEMBL20399613 | 0.77 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL4152950 | 0.76 | RAB9A (0.50) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL13412435 | 0.75 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL1111686 | 0.75 | MAPT (0.47) | POLBKDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL30592770 | 0.75 | MAPT (0.47) | POLBKDM4EASPHKDM8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012389-A1 | Substituted Pyridazines Having Herbicidal Action | BASF SE (DE) | 2013-01-10 | — | — | US | disclosed |
| US-20130012389-A1 | Substituted Pyridazines Having Herbicidal Action | BASF SE (DE) | 2013-01-10 | — | — | US | disclosed |
| EP-2438071-A1 | SUBSTITUTED PYRAZINE (THIO)PYRANS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2011117211-A1 | SUBSTITUTED PYRIDAZINES HAVING HERBICIDAL ACTION | BASF SE (DE) | 2011-09-29 | — | — | WO | disclosed |
| WO-2010139657-A1 | SUBSTITUTED PYRAZINE (THIO)PYRANS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012389-A1 | Substituted Pyridazines Having Herbicidal Action | PNPO, PLPBP, CYP4Z1 | RAB9A 3970/4885SMN1; SMN2 3470/4885NPC1 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.