Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ASPH | Q12797 | 1/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636713 | 0.87 | RAB9A (0.57) | HTTMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL24993602 | 0.82 | TDP1 (0.50) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL784068 | 0.81 | RAB9A (0.60) | HTTMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL2636206 | 0.80 | HTT (0.49) | HTTMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL18824977 | 0.80 | HTR1A (0.46) | HTTMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL2636714 | 0.78 | NPC1 (0.54) | HTTMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29173548 | 0.77 | SCNN1A (0.50) | HTTMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL31214279 | 0.76 | NPSR1 (0.48) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL958881 | 0.76 | NPSR1 (0.48) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13412435 | 0.74 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841298-B2 | Substituted pyrano[2,3-B]pyrazines as herbicides | BASF SE (DE) | 2014-09-23 | — | — | US | disclosed |
| US-20120077678-A1 | Substituted Pyrazine (Thio)Pyrans with a Herbicidal Action | BASF SE (DE) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077678-A1 | Substituted Pyrazine (Thio)Pyrans with a Herbicidal Action | PFAS, TST, TPMT | HTT 604/4885MAPT 1848/4885ALDH1A1 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.