SCHEMBL26375017

SCHEMBL26375017

Cc1ccccc1-c1ccc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.49
RXRA P19793 4/20 0.47
RXRB P28702 4/20 0.47
RXRG P48443 3/20 0.46
PDK2 Q15119 1/20 0.45
TACR1 P25103 8/20 0.44
KIF11 P52732 1/20 0.44
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321771 0.85 KIF11 (0.56) ARPDK2KIF11CA12CA1
SCHEMBL321574 0.80 AR (0.50) ARPDK2
SCHEMBL28222642 0.78 KIF11 (0.70) RXRARXRBRXRGTACR1KIF11
SCHEMBL29551646 0.78 CA12 (0.59) ARPDK2CA12CA1CA2
SCHEMBL4541662 0.78 CA12 (0.59) ARPDK2CA12CA1CA2
SCHEMBL594165 0.77 RXRA (0.55) ARRXRARXRBRXRGKIF11
SCHEMBL2138447 0.76 KIF11 (0.65) RXRARXRBRXRGTACR1KIF11
SCHEMBL21738637 0.76 NR3C1 (0.40) ARRXRARXRBPDK2TACR1
SCHEMBL21738636 0.76 AR (0.39) ARRXRARXRBPDK2TACR1
SCHEMBL3633054 0.76 CA12 (0.61) ARPDK2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 AR 1888/4885RXRA 3881/4885RXRB 3913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.