Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12388145 | 0.86 | CA12 (0.46) | KIF11ARCA12CA1CA2 | |
| SCHEMBL12388711 | 0.86 | CA12 (0.46) | KIF11ARCA12CA1CA2 | |
| SCHEMBL26375017 | 0.85 | AR (0.49) | KIF11ARCA12CA1CA2 | |
| SCHEMBL17840160 | 0.84 | KIF11 (0.68) | KIF11ALDH1A1TSHRBACE1KDM4E | |
| SCHEMBL10304776 | 0.84 | KIF11 (0.47) | KIF11ALDH1A1TSHRBACE1MAPT | |
| SCHEMBL12364956 | 0.84 | CA12 (0.44) | KIF11ARCA12CA1CA2 | |
| SCHEMBL10304812 | 0.82 | KIF11 (0.45) | KIF11BACE1MAPTTP53RAB9A | |
| SCHEMBL8025255 | 0.82 | KIF11 (0.65) | KIF11ALDH1A1TSHRBACE1KDM4E | |
| SCHEMBL3633054 | 0.82 | CA12 (0.61) | ARCA12CA1CA2CA9 | |
| SCHEMBL29551674 | 0.82 | CA12 (0.61) | ARCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426106-B1 | Piperidine and Piperazine derivatives for the treatment of tumours | MERCK PATENT GMBH (DE) | 2013-07-31 | — | — | EP | claimed |
| EP-1700837-B1 | Process for producing 4-(2-methylphenyl)benzotrifluoride | SUMITOMO CHEMICAL CO (JP) | 2008-09-03 | — | — | EP | claimed |
| US-7208645-B2 | Process for producing 4-(2-methylphenyl)benzotrifluoride | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-24 | — | — | US | claimed |
| US-20060211896-A1 | Process for producing 4-(2-methylphenyl)benzotrifluoride | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-21 | — | — | US | claimed |
| EP-1700837-A1 | Process for producing 4-(2-methylphenyl)benzotrifluoride | Sumitomo Chemical Company, Limited (JP) | 2006-09-13 | — | — | EP | claimed |
| CN-113845427-B | Aryl alcohol, aryl ketone, aryl carboxylic acid compound, and synthetic method and application thereof | 华东师范大学 | 2024-06-25 | — | — | CN | disclosed |
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-09-28 | — | — | US | disclosed |
| CN-115433076-A | Method for preparing aromatic acid by metal-free photocatalytic oxidation | 浙江工业大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-111978200-B | Biphenylamide derivative, preparation method and application | 湖北省生物农药工程研究中心 | 2022-09-13 | — | — | CN | disclosed |
| CN-113845427-A | Aryl alcohol, aryl ketone, aryl carboxylic acid compound and synthesis method and application thereof | 华东师范大学 | 2021-12-28 | — | — | CN | disclosed |
| US-11193065-B2 | Liquid crystal composition, method of producing the same, and retardation film constituted from the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-12-07 | — | — | US | disclosed |
| EP-3719004-A1 | PYRIDINIUM SALT AND PEST CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |
| US-20010034459-A1 | Process for preparing 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethyl-biphenyl-2-carboxylic acid from o-tolylmetallates | MEUDT ANDREAS (DE) | 2001-10-25 | — | — | US | disclosed |
| US-20010034459-A1 | Process for preparing 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethyl-biphenyl-2-carboxylic acid from o-tolylmetallates | MEUDT ANDREAS (DE) | 2001-10-25 | — | — | US | disclosed |
| US-20010020110-A1 | Production methods of alpha, alpha, alpha-trifluoromethylphenyl-substituted benzoic acid and intermediate therefor | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1122234-A2 | Production methods of alpha, alpha, alpha-trifluoromethylphenyl-substituted benzoic acid and intermediate therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |
| JP-2001213817-A | METHOD OF PRODUCING 4'-TRIFLUOROMETHYL-2-METHYLBIPHENYL AND 4'-TRIFLUOROMETHYL-BIPHENYL-2-CARBOXYLIC ACID FROM O-TOLYL METALATE | CLARIANT GMBH | 2001-08-07 | — | — | JP | disclosed |
| EP-1112991-A2 | Process for the preparation of 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethylbiphenyl-2-carboxylic acid from o-tolylmetallates | Clariant GmbH (DE) | 2001-07-04 | — | — | EP | disclosed |
| EP-1112991-A2 | Process for the preparation of 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethylbiphenyl-2-carboxylic acid from o-tolylmetallates | Clariant GmbH (DE) | 2001-07-04 | — | — | EP | disclosed |
| EP-1112991-A2 | Process for the preparation of 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethylbiphenyl-2-carboxylic acid from o-tolylmetallates | Clariant GmbH (DE) | 2001-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034459-A1 | Process for preparing 4'-trifluoromethyl-2-methylbiphenyl and 4'-trifluoromethyl-biphenyl-2-carboxylic acid from o-tolylmetallates | ZC3HAV1L, ZRANB2, ZFP3 | KIF11 707/4885AR 3505/4885CA12 2343/4885 |
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | OCIAD1, OCIAD2, SLCO4C1 | KIF11 755/4885AR 1888/4885CA12 3711/4885 |
| US-20010020110-A1 | Production methods of alpha, alpha, alpha-trifluoromethylphenyl-substituted benzoic acid and intermediate therefor | SLC6A11, CYP4F11, SLC39A11 | KIF11 1001/4885AR 4294/4885CA12 1460/4885 |
| US-20060211896-A1 | Process for producing 4-(2-methylphenyl)benzotrifluoride | CYP4F12, GTF3C4, CXXC4 | KIF11 1224/4885AR 4688/4885CA12 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.