Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637724 | 0.89 | TYMP (0.35) | METKDRTYMPLDHAPSD | |
| SCHEMBL2637590 | 0.88 | KDM4E (0.41) | METKDRMAPTMEN1KMT2A | |
| SCHEMBL2637972 | 0.86 | MEN1 (0.41) | LDHAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL2637594 | 0.86 | MAT2A (0.37) | METKDRMAPTMEN1KMT2A | |
| SCHEMBL2637722 | 0.77 | PSD (0.39) | PSDMAPTMEN1KMT2AKDM4E | |
| SCHEMBL2637795 | 0.77 | MEN1 (0.44) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL2637499 | 0.75 | KMT2A (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2638843 | 0.75 | MAPT (0.35) | TYMPPSDMAPTMEN1KMT2A | |
| SCHEMBL2637556 | 0.71 | POLB (0.46) | METKDRPSDMAPTMEN1 | |
| SCHEMBL2637478 | 0.70 | HSP90AA1 (0.47) | LDHAPSDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438070-A1 | GLYCINE B ANTAGONISTS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139483-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | disclosed |