SCHEMBL8190656

SCHEMBL8190656

N[C@H]([C]=O)CC1CCC(O)CC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.34
ENPEP Q07075 2/20 0.34
SHBG P04278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5665177 1.00 ANPEP (0.34) ANPEPENPEPSHBG
SCHEMBL7608856 0.89
SCHEMBL8943205 0.81 CPB2 (0.36) ANPEPENPEP
SCHEMBL2640244 0.81 CPB2 (0.36) ANPEPENPEP
SCHEMBL7375737 0.80 ALOX5 (0.34)
SCHEMBL7375837 0.80
SCHEMBL7418539 0.78 METAP1 (0.37)
SCHEMBL1449256 0.78 METAP1 (0.37)
SCHEMBL3504941 0.78 METAP1 (0.37)
SCHEMBL10583764 0.75 CPN1 (0.42) ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5449612-A Process for identifying candida by means of chromogenic substances SERBIO (FR) 1995-09-12 US claimed
EP-0280610-B1 DIPEPTIDES, PREPARATION PROCESS AND USE IN DOSING PROTEASES SERBIO (FR) 1992-10-21 EP claimed
US-6121239-A SPECIFIED TRI- AND TETRA-PEPTIDES SERBIO (FR) 2000-09-19 US disclosed
EP-0456567-B1 Procedure to determine a plasminogen activator and its inhibitor STAGO DIAGNOSTICA (FR) 1998-01-07 EP disclosed
EP-0476107-B1 PROCESS FOR IDENTIFYING CANDIDA ALBICANS BY MEANS OF CHROMOGENIC SUBSTANCES STAGO DIAGNOSTICA (FR) 1996-06-19 EP disclosed
US-5472851-A Converting plasminogen to plasmin and the assaying plasmin resulting from said conversion; inhibiting plsma proteins alpha2-antiplsmin and alpha2-macroglobulin by contact with metalloproteinase SERBIO (FR) 1995-12-05 US disclosed
US-5449612-A Process for identifying candida by means of chromogenic substances SERBIO (FR) 1995-09-12 US disclosed
EP-0472670-B1 SYMMETRICAL BIPEPTIDES INCLUDING A POLYALKYLENE-GYLCOL GROUP, METHOD OF PREPARATION AND USE IN PROTEASE DETERMINATION SERBIO (FR) 1995-03-29 EP disclosed
EP-0472671-B1 PEPTIDE SUBSTRATES FOR Xa FACTOR IDENTIFICATION SERBIO (FR) 1995-03-15 EP disclosed
US-5225532-A SYMMETRICAL BIPEPTIDES CONTAINING A POLYALKYLENE GLYCOL RESIDUE, METHOD OF PREPARATION AND USE IN THE ASSAY OF PROTEASES SERBIO (FR) 1993-07-06 US disclosed
EP-0280610-B1 DIPEPTIDES, PREPARATION PROCESS AND USE IN DOSING PROTEASES SERBIO (FR) 1992-10-21 EP disclosed
EP-0472671-A1 PEPTIDE SUBSTRATES FOR Xa FACTOR IDENTIFICATION. SERBIO (FR) 1992-03-04 EP disclosed
EP-0456567-A1 Procedure to determine a plasminogen activator and its inhibitor DIAGNOSTICA STAGO (société anonyme) (FR) 1991-11-13 EP disclosed
WO-1991014787-A1 PROCESS FOR IDENTIFYING CANDIDA BY MEANS OF CHROMOGENIC SUBSTANCES SERBIO (FR) 1991-10-03 WO disclosed
WO-1991012263-A1 SYMMETRICAL BIPEPTIDES INCLUDING A POLYALKYLENE-GYLCOL GROUP, METHOD OF PREPARATION AND USE IN PROTEASE DETERMINATION SERBIO (FR) 1991-08-22 WO disclosed
WO-1991012338-A1 PEPTIDE SUBSTRATES FOR Xa FACTOR IDENTIFICATION SERBIO (FR) 1991-08-22 WO disclosed
EP-0280610-A1 Dipeptides, preparation process and use in dosing proteases SERBIO (FR) 1988-08-31 EP disclosed
US-4598043-A Method for quantitatively assaying blood coagulation factor XII in human plasma PENTAPHARM AG (CH) 1986-07-01 US disclosed