SCHEMBL26404497

SCHEMBL26404497

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nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.60
OXER1 Q8TDS5 5/20 0.49
TRPV1 Q8NER1 1/20 0.43
ALDH1A1 P00352 3/20 0.43
LTB4R2 Q9NPC1 2/20 0.43
LTB4R Q15722 1/20 0.43
CMKLR1 Q99788 1/20 0.42
FAAH O00519 4/20 0.42
CYP19A1 P11511 2/20 0.39
RXRA P19793 2/20 0.39
PPARG P37231 2/20 0.39
MAPT P10636 2/20 0.39
FFAR1 O14842 1/20 0.39
F7 P08709 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
F3 P13726 1/20 0.37
PTGS1 P23219 1/20 0.37
KMT2A Q03164 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3411391 1.00 FPR2 (0.60) FPR2OXER1TRPV1ALDH1A1LTB4R2
SCHEMBL26404521 1.00 FPR2 (0.60) FPR2OXER1TRPV1ALDH1A1LTB4R2
SCHEMBL13235773 0.94 FPR2 (0.58) FPR2OXER1TRPV1ALDH1A1LTB4R2
SCHEMBL16675136 0.91 OXER1 (0.54) FPR2OXER1TRPV1ALDH1A1LTB4R2
SCHEMBL17528600 0.91 OXER1 (0.54) FPR2OXER1TRPV1ALDH1A1LTB4R2
SCHEMBL12151577 0.91 OXER1 (0.54) FPR2OXER1TRPV1ALDH1A1LTB4R2
SCHEMBL16675135 0.91 OXER1 (0.54) FPR2OXER1TRPV1ALDH1A1LTB4R2
SCHEMBL3406717 0.91 OXER1 (0.54) FPR2OXER1TRPV1ALDH1A1LTB4R2
SCHEMBL3404679 0.91 OXER1 (0.54) FPR2OXER1TRPV1ALDH1A1LTB4R2
SCHEMBL20085622 0.91 OXER1 (0.54) FPR2OXER1TRPV1ALDH1A1LTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303474-A1 TOTAL SYNTHESES OF SPECIALIZED PRO-RESOLVING MEDIATORS (SPMS), STRUCTURAL ISOMERS AND STRUCTURAL ANALOGS UNIVERSITé LAVAL (CA) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303474-A1 TOTAL SYNTHESES OF SPECIALIZED PRO-RESOLVING MEDIATORS (SPMS), STRUCTURAL ISOMERS AND STRUCTURAL ANALOGS ALOX12, ALOX15, ALOX15B FPR2 43/4885OXER1 50/4885TRPV1 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.