SCHEMBL2640685

SCHEMBL2640685

CCC(C)(C(=O)O)P(=O)(O)O

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
FDPS P14324 12/20 0.36
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
GGPS1 O95749 5/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10704353 0.82 LMNA (0.32) LMNAFDPS
SCHEMBL12931443 0.81 FDPS (0.48) FDPSGGPS1
SCHEMBL2978551 0.80 TSHR (0.35) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL2986483 0.78 ALDH1A1 (0.33) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL871609 0.78 TSHR (0.48) LMNAFDPSTSHRALDH1A1CYP2D6
SCHEMBL1137852 0.78 FDPS (0.40) LMNAFDPSGGPS1
SCHEMBL11296652 0.78 FDPS (0.50) FDPSGGPS1
SCHEMBL11316650 0.76 LMNA (0.35) LMNAFDPSTSHRALDH1A1CYP2D6
SCHEMBL11600783 0.76 TSHR (0.46) LMNAFDPSTSHRALDH1A1CYP2D6
Butane SCHEMBL8954146 0.76 FDPS (0.48) FDPSGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1554330-B1 PARTIALLY ESTER-EXCHANGED SIPM AND PROCESS THEREWITH INVISTA TECH SARL (CH) 2009-03-11 EP claimed
WO-2008137446-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASE TRUSTEES OF BOSTON UNIVERSITY (US) 2008-11-13 WO claimed
EP-1615934-B1 TITANIUM CHELATE DISPERSIONS DU PONT (US) 2007-06-27 EP claimed
CN-116926029-A NADH dependent type L-glufosinate dehydrogenase mutant, construction method and application thereof in preparation of L-glufosinate by enzymatic method 湖南麦肯伟科技有限公司 2023-10-24 CN disclosed
CN-109735583-A A kind of method of single transaminase-catalyzed cascade reaction asymmetric syntheses L-glufosinate-ammonium 浙江工业大学 2019-05-10 CN disclosed
CN-107119084-A A kind of method that utilization transaminase and ethylene synthetase produce L glufosinate-ammoniums 浙江大学 2017-09-01 CN disclosed
CN-101336246-B Phosphonic acid diester derivative and method for producing same PING ZHURUN 2012-11-28 CN disclosed
US-8129557-B2 Phosphonic acid diester derivative and method for producing thereof Nagai, Kazuhiro (JP) 2012-03-06 US disclosed
US-20090163725-A1 PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF HIRATAKE, GOU (JP) 2009-06-25 US disclosed
CN-101336246-A Phosphonic acid diester derivative and method for producing same HIRATAKE JUN (JP) 2008-12-31 CN disclosed
WO-2008137446-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASE TRUSTEES OF BOSTON UNIVERSITY (US) 2008-11-13 WO disclosed
EP-0290169-A2 Diamineplatinum complexes with phosphonocarboxylate and substituted phosphonocarboxylate ligands as antitumor agents ENGELHARD CORPORATION (US) 1988-11-09 EP disclosed
US-4591651-A Process for directly converting an aldehyde into an ethylene ester AGRIFURANE S.A. (FR) 1986-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163725-A1 PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF PPA1, G6PD, PHOSPHO1 LMNA 3690/4885FDPS 53/4885TSHR 2704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.