Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALB | P02768 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | TK1 | P04183 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641184 | 1.00 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL9122198 | 1.00 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL9122200 | 1.00 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL23897378 | 0.82 | TK1 (0.40) | LMNAALBBLMALDH1A1POLB | |
| 4'-Thiothymidine SCHEMBL9520953 | 0.78 | TK1 (0.49) | LMNAALBBLMALDH1A1POLB | |
| 4'-Thiothymidine SCHEMBL23897578 | 0.78 | TK1 (0.49) | LMNAALBBLMALDH1A1POLB | |
| 4'-Thiothymidine SCHEMBL3517588 | 0.78 | TK1 (0.49) | LMNAALBBLMALDH1A1POLB | |
| 4'-Thiothymidine SCHEMBL12642446 | 0.78 | TK1 (0.49) | LMNAALBBLMALDH1A1POLB | |
| 4'-Thiothymidine SCHEMBL6311407 | 0.78 | TK1 (0.49) | LMNAALBBLMALDH1A1POLB | |
| 4'-Thiothymidine SCHEMBL23897630 | 0.78 | TK1 (0.49) | LMNAALBBLMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H08504753-A | — | — | 1996-05-21 | — | — | JP | claimed |
| EP-0658166-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | THE UNIVERSITY OF BIRMINGHAM (GB) | 1995-06-21 | — | — | EP | claimed |
| WO-1994005687-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1994-03-17 | — | — | WO | claimed |