Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4'-Thiothymidine SCHEMBL6266871 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL1942500 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL3517583 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL13083838 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL23897578 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL6311407 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL23897630 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL3517588 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL12642446 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL30381070 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525106-A4 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0525106-A1 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1993-02-03 | — | — | EP | disclosed |