Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4'-Thiothymidine SCHEMBL6266871 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL1942500 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL3517583 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL13083838 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL23897578 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL23897630 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL3517588 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL9520953 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL12642446 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB | |
| 4'-Thiothymidine SCHEMBL30381070 | 1.00 | TK1 (0.49) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202788-A2 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-10-07 | — | — | WO | disclosed |
| US-6949522-B2 | β-2′- or 3′-halonucleosides | PHARMASSET, INC. (US) | 2005-09-27 | — | — | US | disclosed |
| US-20050119286-A1 | BETA-2'-OR 3'-HALONUCLEOSIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-06-02 | — | — | US | disclosed |
| EP-1478322-A2 | Beta-2'-OR 3'-HALONUCLEOSIDES | Pharmasset Limited (BB) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003000200-A2 | β-2'-OR 3'-HALONUCLEOSIDES | PHARMASSET LTD. (BB) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119286-A1 | BETA-2'-OR 3'-HALONUCLEOSIDES | MKI67, EBP, PCNA | TK1 157/4885ALDH1A1 2973/4885LMNA 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.