Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | DRD4 | P21917 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24123767 | 0.83 | MAPT (0.47) | ALDH1A1MAPTMCOLN3DRD2DRD4 | |
| SCHEMBL26407171 | 0.82 | ADRB1 (0.46) | CARM1PRMT6PRMT8ALDH1A1MCOLN3 | |
| SCHEMBL22942152 | 0.74 | CARM1 (0.38) | CARM1PRMT6PRMT8ALDH1A1MAPT | |
| SCHEMBL24327052 | 0.72 | CARM1 (0.39) | CARM1PRMT6PRMT8ALDH1A1MAPT | |
| SCHEMBL7715928 | 0.72 | FFAR4 (0.39) | MAPTGAAMEN1KMT2A | |
| SCHEMBL26407207 | 0.72 | OPRK1 (0.43) | ALDH1A1DRD2DRD4HTTLMNA | |
| SCHEMBL20374468 | 0.71 | GAA (0.44) | ALDH1A1MAPTGAALMNASMN1; SMN2 | |
| SCHEMBL23759702 | 0.71 | CARM1 (0.38) | CARM1PRMT6PRMT8DRD2DRD4 | |
| SCHEMBL26407206 | 0.71 | ACACB (0.41) | CARM1PRMT6PRMT8ALDH1A1MEN1 | |
| SCHEMBL13935733 | 0.71 | MAPT (0.47) | ALDH1A1MAPTMCOLN3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169919-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |