Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339492 | 0.85 | ALOX15 (0.81) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL4883574 | 0.84 | PTPN7 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL2798360 | 0.82 | MEN1 (0.47) | ALDH1A1MEN1MAPTKMT2ATBXAS1 | |
| SCHEMBL166364 | 0.82 | ALOX15 (0.63) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL2642068 | 0.82 | ALOX15 (0.63) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL9832704 | 0.82 | ALOX15 (0.63) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL27869587 | 0.81 | ALOX15 (0.57) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL436174 | 0.80 | MAPT (0.60) | ALOX15ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL10399496 | 0.80 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL4781395 | 0.80 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376218-B1 | Racemization free attachment of amino acids to solid phase | PERSEPTIVE BIOSYSTEMS INC (US) | 1999-02-24 | — | — | EP | claimed |
| EP-0434034-A1 | Oxazole derivatives | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | claimed |
| EP-0376218-A2 | Racemization free attachment of amino acids to solid phase | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1990-07-04 | — | — | EP | claimed |
| US-9278951-B2 | Azolium and purinium salt anticancer and antimicrobial agents | THE UNIVERSITY OF AKRON (US) | 2016-03-08 | — | — | US | disclosed |
| US-9278951-B2 | Azolium and purinium salt anticancer and antimicrobial agents | THE UNIVERSITY OF AKRON (US) | 2016-03-08 | — | — | US | disclosed |
| US-9278951-B2 | Azolium and purinium salt anticancer and antimicrobial agents | THE UNIVERSITY OF AKRON (US) | 2016-03-08 | — | — | US | disclosed |
| US-9212196-B2 | Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof | UNIVERSITE PARIS DESCARTES (FR) | 2015-12-15 | — | — | US | disclosed |
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | THE UNIVERSITY OF AKRON | 2014-05-22 | — | — | US | disclosed |
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | THE UNIVERSITY OF AKRON | 2014-05-22 | — | — | US | disclosed |
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | THE UNIVERSITY OF AKRON | 2014-05-22 | — | — | US | disclosed |
| US-20140107078-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | UNIVWESITE D"AUVERGNE (FR) | 2014-04-17 | — | — | US | disclosed |
| EP-0376218-B1 | Racemization free attachment of amino acids to solid phase | PERSEPTIVE BIOSYSTEMS INC (US) | 1999-02-24 | — | — | EP | disclosed |
| EP-0786701-A1 | RESIST COMPOSITION | NIPPON ZEON CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-5418250-A | Hypotensive | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-23 | — | — | US | disclosed |
| US-5262540-A | FOR INHIBITION OF BLOOD PLATELET AGGREGATION IN MAMMALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-11-16 | — | — | US | disclosed |
| US-5187270-A | Solid phase synthesis of peptides using the reaction product of an N-protected amino acid and a 2,4-dichlorophenyl (4-halo methylphenoxy)acetate; efficiency; purity; kinetics | MILLIPORE CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |
| US-5185351-A | Hypotensive agents; for treatment of congestive heart failure, renal failure and glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0434034-A1 | Oxazole derivatives | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0376218-A2 | Racemization free attachment of amino acids to solid phase | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1990-07-04 | — | — | EP | disclosed |
| US-4461905-A | THROMBOXANE SYNTHETASE INHIBITOR INTERMEDIATE | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | PCNA, ITPA, MPI | ALOX15 4639/4885ALDH1A1 3117/4885SMN1; SMN2 3715/4885 |
| US-20140107078-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | HCAR3, HRH3, SSTR3 | ALOX15 2716/4885ALDH1A1 1395/4885SMN1; SMN2 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.