Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.42 |
| ▸ | S100B | P04271 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27548555 | 0.82 | HTR7 (0.62) | ALDH1A1HTTMAPTADRB1HTR1A | |
| SCHEMBL487317 | 0.82 | LMNA (0.59) | MEN1ALDH1A1KMT2AKDM4EHSD17B10 | |
| SCHEMBL26423291 | 0.82 | ADRA2C (0.65) | MEN1ALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL22685038 | 0.81 | ALDH1A1 (0.59) | MEN1ALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL29053019 | 0.80 | ADRA2C (0.62) | MEN1ALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL30468954 | 0.80 | ADRA2C (0.62) | MEN1ALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL12389862 | 0.79 | VCP (0.49) | MEN1ALDH1A1KMT2AAGXTHTT | |
| SCHEMBL533024 | 0.76 | ADRA2C (0.68) | MEN1ALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL255378 | 0.74 | ALDH1A1 (0.52) | MEN1ALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL1397693 | 0.74 | ADRA2C (0.66) | MEN1ALDH1A1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |