Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22065273 | 0.75 | ALDH1A1 (0.54) | ALDH1A1PKMKMT2AMEN1LMNA | |
| SCHEMBL17318640 | 0.75 | RXFP1 (0.58) | ALDH1A1SRCKMT2ALMNAMAPT | |
| SCHEMBL20631694 | 0.73 | ALDH1A1 (0.59) | ALDH1A1PKMKMT2AMEN1LMNA | |
| SCHEMBL17318619 | 0.72 | NPC1 (0.58) | ALDH1A1SRCKMT2AMEN1LMNA | |
| SCHEMBL17318647 | 0.72 | DDX3X (0.64) | SRCKMT2AMEN1MAPTNPC1 | |
| SCHEMBL31061167 | 0.72 | SRC (1.00) | ALDH1A1SRCKMT2AMEN1LMNA | |
| SCHEMBL1543267 | 0.72 | ALDH1A1 (0.68) | ALDH1A1PKMKMT2AMEN1LMNA | |
| SCHEMBL7489058 | 0.71 | SRC (0.74) | ALDH1A1SRCKMT2AMEN1LMNA | |
| SCHEMBL14825055 | 0.71 | RAB9A (0.58) | ALDH1A1PKMKMT2AMEN1LMNA | |
| SCHEMBL5835649 | 0.71 | CCNE1 (0.57) | ALDH1A1SRCKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128972-A1 | Anat Inhibitors and Methods of Use Thereof | Atomwise Inc. | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128972-A1 | Anat Inhibitors and Methods of Use Thereof | AANAT, CHAT, NAT1 | ALDH1A1 616/4885PKM 3401/4885SRC 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.