SCHEMBL26426643

SCHEMBL26426643

CN1CCCC(COC(=O)c2cc(I)cc(I)c2I)C1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRNB4 P30926 10/20 0.56
CHRNA3 P32297 10/20 0.56
CHRNB2 P17787 9/20 0.56
CHRNA4 P43681 9/20 0.56
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
IRAK4 Q9NWZ3 1/20 0.39
HTR4 Q13639 4/20 0.38
ACHE P22303 1/20 0.37
CHRM3 P20309 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26426646 0.86 HTR4 (0.49) CHRNB4CHRNA3CHRNB2CHRNA4HDAC1
SCHEMBL21705230 0.78 CHRNB4 (0.55) CHRNB4CHRNA3CHRNB2CHRNA4HDAC1
SCHEMBL26427846 0.77 HTR4 (0.38) HDAC1HDAC2HTR4ACHECHRM3
SCHEMBL26426645 0.76 CHRM3 (0.43) CHRNB2CHRNA4CHRM3
SCHEMBL28255620 0.74 CHRNB4 (0.72) CHRNB4CHRNA3CHRNB2CHRNA4CHRM3
SCHEMBL26834873 0.74 CHRM2 (0.37) HDAC1HDAC2HTR4ACHECHRM3
SCHEMBL21783772 0.73 HRH3 (0.49) HTR4
SCHEMBL21705754 0.72 KMT2A (0.50) HTR4
SCHEMBL26427856 0.72 ATM (0.53) CHRM3
SCHEMBL22277818 0.71 SLC6A2 (0.34) CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11835859-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-20230129578-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230129578-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed