SCHEMBL264283

SCHEMBL264283

O=C1[N]N(c2ccc([N+](=O)[O-])cc2)C(=O)c2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.47
ALOX12 P18054 2/20 0.47
HPGD P15428 1/20 0.47
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
MAPT P10636 6/20 0.47
GAA P10253 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
IDO1 P14902 1/20 0.46
TDO2 P48775 1/20 0.46
AR P10275 1/20 0.44
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
ALDH1A1 P00352 4/20 0.43
NPC1 O15118 3/20 0.43
LMNA P02545 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
RAB9A P51151 2/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263572 0.80 CYP1A2 (0.47) SCN2AMEN1KMT2AMAPTGAA
SCHEMBL1973251 0.77 SCN2A (1.00) SCN2AMEN1KMT2AMAPTGAA
SCHEMBL30118348 0.77 SCN2A (1.00) SCN2AMEN1KMT2AMAPTGAA
SCHEMBL9305057 0.70 MEN1 (0.62) SCN2AL3MBTL1ALOX12HPGDMEN1
SCHEMBL6738545 0.68 SCN2A (0.47) SCN2AL3MBTL1ALOX12MEN1KMT2A
SCHEMBL10189781 0.68 CA12 (0.64) SCN2AL3MBTL1ALOX12HPGDMEN1
SCHEMBL17550101 0.68 CA1 (0.62) SCN2AL3MBTL1MAPTGAAALDH1A1
SCHEMBL28360722 0.68 NPC1 (0.68) SCN2AMEN1KMT2AMAPTGAA
SCHEMBL5707683 0.68 SCN2A (0.69) SCN2AHPGDMAPTGAANPSR1
SCHEMBL29531485 0.68 CA1 (0.62) SCN2AL3MBTL1MAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1655070-B1 OXIDATION CATALYST ASAHI KASEI CHEMICALS CORP (JP) 2015-07-15 EP disclosed
US-8133834-B2 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-03-13 US disclosed
US-20100069670-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-03-18 US disclosed
US-20060229471-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2006-10-12 US disclosed
EP-1655070-A1 OXIDATION CATALYST Asahi Kasei Chemicals Corporation (JP) 2006-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069670-A1 Oxidation catalyst PPOX, SOD1, HAO2 SCN2A 2661/4885L3MBTL1 4444/4885ALOX12 208/4885
US-20060229471-A1 Oxidation catalyst PPOX, SOD1, HAO2 SCN2A 2661/4885L3MBTL1 4444/4885ALOX12 208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.