SCHEMBL2642848

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10060475	0.87	ALDH1A1 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL10060466	0.80	CA12 (0.46)	MAPTHTTPOLBCA1CA2
	SCHEMBL178444	0.78	GAA (0.56)	ALDH1A1MAPTGAAKDM4EHTT
	SCHEMBL14520771	0.78	ENPP2 (0.52)	—
	SCHEMBL2657775	0.78	ALDH1A1 (0.36)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL21959011	0.76	LOX (0.39)	L3MBTL1ALDH1A1ABL1MAPTKDM4E
	SCHEMBL1811878	0.76	ALDH1A1 (0.48)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL152957	0.76	MMP2 (0.53)	CA1CA2CA9
	SCHEMBL1368959	0.76	CA1 (0.48)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL2646286	0.76	CA1 (0.47)	ALDH1A1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.