SCHEMBL2657775

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10060475	0.89	ALDH1A1 (0.40)	ALDH1A1PSEN1PSEN2APH1BNCSTN
	SCHEMBL10060466	0.82	CA12 (0.46)	CA1CA2CA9MMP1MMP13
	SCHEMBL178444	0.80	GAA (0.56)	ALDH1A1CA1CA2CA5ACA7
	SCHEMBL14520771	0.80	ENPP2 (0.52)	—
	SCHEMBL1811878	0.78	ALDH1A1 (0.48)	ALDH1A1PSEN1PSEN2APH1BNCSTN
	SCHEMBL2642848	0.78	L3MBTL1 (0.37)	ALDH1A1PSEN1PSEN2APH1BNCSTN
	SCHEMBL1368959	0.78	CA1 (0.48)	ALDH1A1PSEN1PSEN2APH1BNCSTN
	SCHEMBL2646286	0.78	CA1 (0.47)	ALDH1A1CA1CA2CA9MMP1
	SCHEMBL2646217	0.78	ENPP2 (0.56)	ALDH1A1CA1CA2CA5ACA7
	SCHEMBL152957	0.78	MMP2 (0.53)	CA1CA2CA9MMP1MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.