Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112428 | 0.72 | KDM4E (0.49) | AURKAALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL2814618 | 0.67 | PIN1 (0.54) | AURKAALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL23835762 | 0.66 | KDM4E (0.49) | AURKAALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL24450252 | 0.66 | SMN1; SMN2 (0.52) | AURKAALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL25789859 | 0.63 | NAMPT (0.58) | SMN1; SMN2KDM4ENAMPTHPSEKMT2A | |
| SCHEMBL23836090 | 0.63 | KDM5A (0.51) | ALDH1A1SMN1; SMN2KDM4EHPGDPDE5A | |
| SCHEMBL7249651 | 0.63 | SMN1; SMN2 (0.50) | AURKAALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL34462940 | 0.63 | SMN1; SMN2 (0.50) | AURKAALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL879284 | 0.63 | ALDH1A1 (0.50) | AURKAALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL1170780 | 0.62 | ALDH1A1 (0.68) | AURKAALDH1A1SMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230130598-A1 | PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230130598-A1 | PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS | SARS1, TPI1, TPMT | AURKA 958/4885ALDH1A1 1430/4885SMN1; SMN2 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.