Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22877348 | 0.88 | TSHR (0.39) | L3MBTL1TSHREGFRSMN1; SMN2ALDH1A1 | |
| SCHEMBL22877184 | 0.80 | POLB (0.44) | L3MBTL1SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL26429627 | 0.79 | POLB (0.40) | EGFRSMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL26429715 | 0.79 | POLB (0.40) | EGFRSMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL26705254 | 0.77 | POLB (0.42) | L3MBTL1SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL26429458 | 0.77 | ALDH1A1 (0.40) | L3MBTL1TSHRSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL26429687 | 0.70 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL22877375 | 0.70 | POLB (0.40) | EGFRALDH1A1POLBCYP2D6LMNA | |
| SCHEMBL22877204 | 0.70 | POLB (0.40) | EGFRALDH1A1POLBCYP2D6LMNA | |
| SCHEMBL26429691 | 0.69 | LTB4R (0.41) | L3MBTL1TSHRSMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639340-B2 | Substituted chromanes, analogs thereof, and methods of use and synthesis | NORTHWESTERN UNIVERSITY (US) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639340-B2 | Substituted chromanes, analogs thereof, and methods of use and synthesis | TYR, ME1, PNPO | L3MBTL1 1006/4885TSHR 861/4885EGFR 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.