Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22877184 | 0.94 | POLB (0.44) | POLBALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL26429458 | 0.89 | ALDH1A1 (0.40) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL22877348 | 0.86 | TSHR (0.39) | POLBALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL26429710 | 0.77 | L3MBTL1 (0.38) | POLBALDH1A1LMNACYP1A2KMT2A | |
| SCHEMBL26429453 | 0.73 | MTNR1A (0.39) | ALDH1A1LMNACYP1A2TDP1HPGD | |
| SCHEMBL26705039 | 0.73 | POLB (0.39) | POLBALDH1A1LMNANPC1 | |
| SCHEMBL26429440 | 0.72 | CYP2D6 (0.40) | ALDH1A1LMNATDP1KDM4EHPGD | |
| SCHEMBL22992514 | 0.69 | POLB (0.47) | POLBALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL22992503 | 0.69 | POLB (0.47) | POLBALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL26429429 | 0.68 | SLC6A2 (0.37) | ALDH1A1MEN1KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339879-A1 | SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS | NORTHWESTERN UNIVERSITY | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339879-A1 | SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS | TYR, ME1, PNPO | POLB 1799/4885ALDH1A1 444/4885LMNA 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.