Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.31 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 3/20 | 0.30 |
| ▸ | KLK1 | P06870 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26436052 | 0.92 | POLB (0.33) | FPR1FPR2POLBF11KLK1 | |
| SCHEMBL26435246 | 0.89 | EPHX2 (0.38) | POLBMEN1MAPTKMT2ADDB1 | |
| SCHEMBL31115915 | 0.89 | EPHX2 (0.38) | POLBMEN1MAPTKMT2ADDB1 | |
| SCHEMBL26435942 | 0.88 | GRM4 (0.35) | MAPTDDB1CRBNGSPT1F11 | |
| SCHEMBL30407271 | 0.87 | FPR1 (0.43) | FPR1FPR2POLBMEN1LMNA | |
| SCHEMBL26087705 | 0.87 | FPR1 (0.43) | FPR1FPR2POLBMEN1LMNA | |
| SCHEMBL26435813 | 0.87 | FPR1 (0.43) | FPR1FPR2POLBMEN1LMNA | |
| SCHEMBL26436126 | 0.85 | RIPK1 (0.34) | FPR1FPR2DDB1CRBNGSPT1 | |
| SCHEMBL30407282 | 0.85 | F11 (0.35) | FPR1FPR2POLBDDB1CRBN | |
| SCHEMBL26435820 | 0.85 | F11 (0.35) | FPR1FPR2POLBDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |