Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23983601 | 0.80 | HRH3 (0.54) | HRH3HRH4 | |
| SCHEMBL25000799 | 0.79 | HRH3 (0.53) | HRH3HRH4FDPS | |
| SCHEMBL502104 | 0.75 | PKM (0.52) | HRH3HRH4FDPSPKM | |
| SCHEMBL20906875 | 0.74 | HRH3 (0.59) | HRH3HRH4FDPS | |
| SCHEMBL1031431 | 0.74 | — | — | |
| SCHEMBL1723732 | 0.72 | HRH3 (0.88) | HRH3HRH4 | |
| SCHEMBL25460713 | 0.72 | FDPS (0.49) | HRH3HRH4FDPSPKM | |
| SCHEMBL25039174 | 0.71 | TAAR1 (0.46) | HRH3HRH4 | |
| SCHEMBL26586059 | 0.71 | HRH3 (0.55) | HRH3HRH4 | |
| SCHEMBL26579852 | 0.71 | HRH3 (0.55) | HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11638760-B2 | Pyrrolobenzodiazepine antibody conjugates | MERSANA THERAPEUTICS, INC. (US) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11638760-B2 | Pyrrolobenzodiazepine antibody conjugates | GABRA4, GABRA1, GABRA2 | HRH3 257/4885HRH4 172/4885FDPS 4758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.