Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662131 | 0.91 | LMNA (0.51) | LMNACYP3A4CYP1A2MAOASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL2643044 | 0.83 | DPP4 (0.50) | DPP4DPP7LMNACYP3A4CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL27739872 | 0.83 | DPP4 (0.50) | DPP4DPP7LMNACYP3A4CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL2642916 | 0.83 | DPP4 (0.50) | DPP4DPP7LMNACYP3A4CYP1A2 | |
| SCHEMBL2643880 | 0.81 | PDK1 (0.40) | DPP4DPP7LMNACYP3A4CYP1A2 | |
| SCHEMBL2643030 | 0.80 | ESR1 (0.49) | LMNACYP3A4CYP1A2MAOASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4699009 | 0.77 | DPP4 (0.46) | DPP4DPP7LMNACYP3A4CYP1A2 | |
| SCHEMBL2643017 | 0.74 | ESR1 (0.43) | LMNACYP3A4CYP1A2MAOAPDK1 | |
| Ethyl Benzoate SCHEMBL27530082 | 0.73 | SMN1; SMN2 (0.58) | LMNACYP3A4CYP1A2MAOASMN1; SMN2 | |
| SCHEMBL11251092 | 0.72 | CASR (0.55) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088070-A1 | Pyrazole derivatives, compositions containing such compounds and methods of use | PARMEE EMMA R | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088070-A1 | Pyrazole derivatives, compositions containing such compounds and methods of use | PC, GOT2, PNLIP | DPP4 13/4885DPP7 14/4885LMNA 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.