Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.40 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.40 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.40 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.40 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.40 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.40 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.40 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379369 | 0.83 | MCL1 (0.52) | MCL1GLASTING1TTRATP1A1 | |
| SCHEMBL6517159 | 0.81 | TTR (0.52) | MCL1TTRSNCANFKB1MEN1 | |
| SCHEMBL29945017 | 0.79 | MAOA (0.61) | GLATTRMAOAKDM4ENPC1 | |
| SCHEMBL13395991 | 0.73 | GLA (0.62) | MCL1GLASTING1ATP1A1ATP1B1 | |
| SCHEMBL18799361 | 0.73 | MCL1 (0.42) | MCL1MAOAELANEPRKDCESR2 | |
| SCHEMBL4510654 | 0.72 | TTR (0.60) | TTRSUMO2SUMO1SENP7SENP3 | |
| SCHEMBL8711628 | 0.71 | MAOA (0.64) | GLATTRMAOAMEN1KMT2A | |
| SCHEMBL13308662 | 0.71 | GLA (0.46) | MCL1GLASTING1TTRATP1A1 | |
| SCHEMBL12531491 | 0.71 | ELANE (0.45) | TTRELANEMEN1KMT2AMYC | |
| SCHEMBL1611920 | 0.71 | CYP2A6 (0.55) | MCL1MAOAELANEPRKDCESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230130102-A1 | Na/K-ATPase LIGANDS AND USE THEREOF FOR TREATMENT OF CANCER | MARSHALL UNIVERSITY RESEARCH CORPORATION | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230130102-A1 | Na/K-ATPase LIGANDS AND USE THEREOF FOR TREATMENT OF CANCER | ATP1A1, ATP1A2, ATP4A | MCL1 2849/4885GLA 2273/4885STING1 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.