Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23490927 | 0.89 | PSEN1 (0.35) | KMT2ADDB1CRBNKDM1APSEN1 | |
| SCHEMBL21452111 | 0.88 | RORC (0.43) | DDB1CRBNPSEN1PSEN2APH1B | |
| SCHEMBL21451897 | 0.88 | HDAC4 (0.39) | KMT2AL3MBTL1DDB1CRBNPSEN1 | |
| SCHEMBL21452380 | 0.87 | OPRM1 (0.39) | DDB1CRBNTSHRRORC | |
| SCHEMBL21452186 | 0.86 | RORC (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21452185 | 0.86 | RORC (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21452181 | 0.86 | RORC (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21452133 | 0.86 | SLC6A4 (0.41) | KMT2A | |
| SCHEMBL21452019 | 0.85 | DRD2 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21452397 | 0.85 | HDAC4 (0.37) | KMT2AL3MBTL1DDB1CRBNKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12466782-B2 | Arylcyclohexylamine derivatives and process for preparing same | Technische Hochschule Köln (DE) | 2025-11-11 | — | — | US | disclosed |
| US-20230139975-A1 | Arylcyclohexylamine derivatives and process for preparing same | Technische Hochschule Köln (DE) | 2023-05-04 | — | — | US | disclosed |
| US-20230139975-A1 | Arylcyclohexylamine derivatives and process for preparing same | Technische Hochschule Köln (DE) | 2023-05-04 | — | — | US | disclosed |
| EP-4114821-A1 | ARYLCYCLOHEXYLAMINE DERIVATIVES AND PROCESS FOR PREPARING SAME | Technische Hochschule Köln (DE) | 2023-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12466782-B2 | Arylcyclohexylamine derivatives and process for preparing same | DDC, AADAT, SNCA | KMT2A 1368/4885L3MBTL1 3838/4885DDB1 1385/4885 |
| US-20230139975-A1 | Arylcyclohexylamine derivatives and process for preparing same | DDC, AADAT, SNCA | KMT2A 1368/4885L3MBTL1 3838/4885DDB1 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.