Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320640 | 0.89 | ALDH1A1 (0.60) | MAPTALDH1A1TP53MAPK1LMNA | |
| SCHEMBL26099431 | 0.84 | MAPT (0.70) | MAPTALDH1A1TP53MAPK1LMNA | |
| SCHEMBL2315847 | 0.81 | ALDH1A1 (0.53) | MAPTALDH1A1MAPK1LMNATSHR | |
| SCHEMBL2321932 | 0.81 | ALDH1A1 (0.50) | MAPTALDH1A1TP53MAPK1LMNA | |
| SCHEMBL2318191 | 0.80 | DRD2 (0.43) | MAPTALDH1A1TP53MAPK1LMNA | |
| SCHEMBL2319375 | 0.80 | ALDH1A1 (0.56) | MAPTALDH1A1MAPK1LMNATSHR | |
| SCHEMBL2322437 | 0.80 | FKBP1A (0.55) | ALDH1A1TP53MAPK1LMNATSHR | |
| SCHEMBL2320616 | 0.80 | ALDH1A1 (0.41) | MAPTALDH1A1TP53MAPK1LMNA | |
| SCHEMBL2321536 | 0.79 | MAPT (0.48) | MAPTALDH1A1TP53MAPK1LMNA | |
| SCHEMBL2449912 | 0.79 | ALDH1A1 (0.45) | MAPTALDH1A1TP53MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2023-05-04 | — | — | US | disclosed |
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | G6PD, QDPR, FASN | MAPT 1034/4885ALDH1A1 1569/4885TP53 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.