Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130583 | 0.85 | CXCR2 (0.48) | ADORA2AADORA1IDO1KMONPY5R | |
| SCHEMBL2944949 | 0.83 | MAPK13 (0.49) | ADORA1IDO1KMONPY5RCXCR2 | |
| SCHEMBL31305411 | 0.83 | MAPK13 (0.49) | ADORA1IDO1KMONPY5RCXCR2 | |
| SCHEMBL15029191 | 0.82 | IDO1 (0.47) | ADORA2AADORA1IDO1METAP2XDH | |
| SCHEMBL29662878 | 0.81 | MAPK14 (0.53) | ENPP3IDO1METAP2XDHPIN1 | |
| SCHEMBL17231794 | 0.81 | RAB9A (0.49) | ADORA2AADORA1ENPP3IDO1METAP2 | |
| SCHEMBL26467067 | 0.81 | ACHE (0.48) | IDO1METAP2XDHPIN1NPC1 | |
| SCHEMBL31659868 | 0.81 | ACHE (0.48) | IDO1METAP2XDHPIN1NPC1 | |
| SCHEMBL8365173 | 0.78 | AHR (0.61) | ENPP3RAB9ARPA1 | |
| SCHEMBL28404729 | 0.77 | NPY5R (0.59) | ADORA2ANPY5RNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |
| EP-4173485-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-03 | — | — | EP | disclosed |