Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923944 | 0.82 | CYP19A1 (0.52) | XDHMMP2MMP9MMP8MAPT | |
| SCHEMBL29703894 | 0.80 | MAPT (0.57) | MMP2MMP9MMP8MAPTMMP13 | |
| SCHEMBL2028396 | 0.80 | ADH5 (0.32) | — | |
| SCHEMBL3164611 | 0.80 | MAPT (0.57) | MMP2MMP9MMP8MAPTMMP13 | |
| SCHEMBL2738746 | 0.78 | CYP3A4 (0.47) | MAPTCASP3LMNAMEN1POLB | |
| SCHEMBL13411813 | 0.78 | ADH5 (0.36) | — | |
| SCHEMBL5311953 | 0.78 | MAPT (0.60) | XDHMAPTLMNAMEN1POLB | |
| SCHEMBL5349749 | 0.77 | MAPT (0.39) | XDHMAPTNPC1RAB9AHTT | |
| SCHEMBL31377032 | 0.76 | KDM4E (0.49) | MAPTCASP3GAALMNAMEN1 | |
| SCHEMBL12821539 | 0.76 | KDM4E (0.49) | MAPTCASP3GAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 799 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658396-A1 | BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS | Arrowhead Pharmaceuticals, Inc. (US) | 2025-12-10 | — | — | EP | claimed |
| US-12264174-B2 | Process for preparing imetelstat | GERON CORPORATION (US) | 2025-04-01 | — | — | US | claimed |
| WO-2025038661-A1 | OLIGONUCLEOTIDE SYNTHESIS METHODS | Arrowhead Pharmaceuticals, Inc. (US) | 2025-02-20 | — | — | WO | claimed |
| WO-2024163644-A1 | BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS | Arrowhead Pharmaceuticals, Inc. (US) | 2024-08-08 | — | — | WO | claimed |
| US-20240262854-A1 | Process for Preparing Imetelstat | BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT (GB) | 2024-08-08 | — | — | US | claimed |
| US-11912734-B2 | Solid-phase synthesis of oligonucleotides containing N6-(2-deoxy-alpha,beta-derythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine (Fapy⋅dG) | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-27 | — | — | US | claimed |
| CN-117106189-A | Metal organic framework artificial hydrolase and preparation method and application thereof | 华南理工大学 | 2023-11-24 | — | — | CN | claimed |
| US-20230312630-A1 | PHOSPHORAMIDITE SYNTHESIS ON-DEMAND | AARHUS UNIVERSITET (DK) | 2023-10-05 | — | — | US | claimed |
| CN-110891961-B | Improved process for the preparation of imaelstat | 美国杰龙生物医药公司 | 2023-06-30 | — | — | CN | claimed |
| EP-4182325-A1 | PHOSPHORAMIDITE SYNTHESIS ON-DEMAND | Aarhus Universitet (DK) | 2023-05-24 | — | — | EP | claimed |
| EP-1017703-A2 | PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | Nanogen Recognomics GmbH (DE) | 2000-07-12 | — | — | EP | claimed |
| US-6048975-A | USE OF DANSYLETHOXYCARBONYL GROUP AS BASE-LABILE 5'-HYDROXYL PROTECTIVE GROUP; EASE OF DETECTION AND EASE OF ELIMINATION WITH BY-PRODUCT INHIBITION FOR HIGH YIELD SYNTHESIS IN VERY SMALL QUANTITIES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-04-11 | — | — | US | claimed |
| WO-1999052923-A2 | METHOD FOR THE PRODUCTION OF PENTOPYRANOSYL NUCLEOSIDES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-10-21 | — | — | WO | claimed |
| US-5945524-A | NUCLEOSIDE WITH DANSYLETHOXYCARBONYL GROUP AS BASE-LABILE 5'-HYDROXYL PROTECTIVE GROUP; FOR EFFICIENT SYNTHESIS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | claimed |
| WO-1999015539-A2 | PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | claimed |
| EP-0766688-A4 | SYNTHESIS OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 1998-12-30 | — | — | EP | claimed |
| WO-1998016540-A1 | IMPROVED COUPLING ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | PROLIGO LLC (US) | 1998-04-23 | — | — | WO | claimed |
| EP-0766688-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1997-04-09 | — | — | EP | claimed |
| US-5571902-A | OLIGOMERIZATION IN THE PRESENCE OF TETRAZOLE COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1996-11-05 | — | — | US | claimed |
| WO-1995032980-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1995-12-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312630-A1 | PHOSPHORAMIDITE SYNTHESIS ON-DEMAND | RNGTT, PPA1, PNP | XDH 2256/4885MMP2 4238/4885MMP9 4330/4885 |
| US-20240262854-A1 | Process for Preparing Imetelstat | TERT, RNGTT, TRMT1L | XDH 3328/4885MMP2 4407/4885MMP9 4287/4885 |
| US-12264174-B2 | Process for preparing imetelstat | TERT, RNGTT, TRMT1L | XDH 3328/4885MMP2 4407/4885MMP9 4287/4885 |
| US-11912734-B2 | Solid-phase synthesis of oligonucleotides containing N6-(2-deoxy-alpha,beta-derythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine (Fapy⋅dG) | DPYD, TYMP, RNGTT | XDH 2233/4885MMP2 4139/4885MMP9 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.